Tag: Pharmacoresistance

Approximately 30% of people with epilepsy have cases classified as drug-resistant because they continue to have seizures despite treatment [1.2.5]. The question of *can epilepsy medication become less effective?* is a critical concern for many, as effectiveness can wane for various reasons.

For approximately 30% of people with epilepsy, medications lose their effectiveness over time, raising the question: **Can you build a tolerance to epilepsy medication?**. This phenomenon is a form of drug resistance, where the body's adaptive changes can cause a previously effective antiseizure medication (ASM) to become less powerful, leading to a return of seizures.