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Tag: Plasma clearance

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Understanding the Pharmacokinetics: At what time will 99% of the drug be cleared from the plasma?

2 min read
For most medications that follow first-order kinetics, approximately 99% of the drug is cleared from the plasma after seven half-lives. This critical pharmacokinetic principle, based on the drug's half-life, helps predict the duration of a drug's therapeutic effects and the time required for complete elimination, answering the question of at what time will 99% of the drug be cleared from the plasma.