Unlocking the Mystery: How Does Pyrazinamide Work to Fight Tuberculosis?
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4 min read
The addition of pyrazinamide to combination therapies in the 1970s famously reduced the duration of tuberculosis treatment from over a year to just six months. Its sterilizing activity against persistent, non-replicating bacteria makes it an essential drug, and understanding **how does pyrazinamide work** has been a decades-long scientific puzzle.