Is polymyxin B sulfate toxic? Risks and safe administration
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4 min read
Historically, concerns over significant nephrotoxicity and neurotoxicity led to the reduced use of polymyxin B sulfate. However, the increasing threat of multidrug-resistant (MDR) Gram-negative bacteria has prompted its re-evaluation and reintroduction into clinical practice, with current research indicating a less severe toxicity profile under modern management.
