Tag: Potassium depletion

While often prescribed for its powerful anti-inflammatory effects, prednisone may cause muscle problems, and many people report that it can cause leg cramps. This is frequently linked to its impact on electrolyte balance and muscle function.

According to anecdotal reports and medical literature, muscle cramps, particularly in the legs, are a recognized side effect associated with the use of corticosteroids like prednisone. For many patients, these painful spasms can be a frustrating and disruptive consequence of a medication vital for managing inflammatory and autoimmune conditions. Understanding the physiological reasons behind this adverse effect is the first step toward effective management and relief.