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Tag: Ppa

Explore our medication guides and pharmacology articles within this category.

Why was Drixoral Banned?: The Phenylpropanolamine Controversy

4 min read
In the year 2000, the U.S. Food and Drug Administration (FDA) issued a public health advisory concerning the popular decongestant ingredient phenylpropanolamine (PPA), which led to the banning of many over-the-counter products, including certain formulations of Drixoral. This decision was based on new scientific evidence linking PPA to an increased risk of hemorrhagic stroke, a severe and potentially life-threatening side effect.

What ingredient was removed from Alka-Seltzer?

3 min read
In 2000, Bayer removed Phenylpropanolamine (PPA) from its Alka-Seltzer Plus formulations following an FDA advisory [1.2.8, 1.2.2]. This article answers: What ingredient was removed from Alka-Seltzer and why was this once-common decongestant taken off the market?

What is norephedrine used for? An investigation into its history, risks, and modern application

4 min read
Between 200 and 500 strokes per year among users aged 18 to 49 were estimated to be caused by products containing phenylpropanolamine (norephedrine), leading to its withdrawal from the market around 2000. This substance, also known as PPA, had a complex history of use, but its association with severe health risks has since redefined what is norephedrine used for in modern medicine.

Is Naldecon Still Available? The Story of a Discontinued Medication

4 min read
In November 2000, the FDA issued a public health warning and requested that drug companies discontinue marketing products containing phenylpropanolamine (PPA), a key ingredient in Naldecon [1.6.2, 1.6.7]. So, the answer to 'Is Naldecon still available?' is no, not in its original formulation.

What is Propalin for humans?: A Guide to the Discontinued Medication

3 min read
In November 2000, the U.S. Food and Drug Administration (FDA) issued a public health advisory recommending against the use of products containing phenylpropanolamine (PPA) due to an increased risk of hemorrhagic stroke. This included medications whose active ingredient was the same as the veterinary drug Propalin, meaning Propalin is definitively not for humans.

What is the drug propanolamine used for? Unpacking the History and Safety of Phenylpropanolamine

4 min read
Following a 2000 U.S. Food and Drug Administration (FDA) public health advisory, the drug formerly known by the misspelling **propanolamine**, correctly identified as phenylpropanolamine, was withdrawn for human consumption due to the increased risk of hemorrhagic stroke. Today, while no longer available for human use in many countries, it continues to be prescribed in veterinary medicine for certain conditions.