Tag: Prochlorperazine

Many prescription medications serve multiple purposes, and a classic example lies within the overlap of antiemetics and antipsychotics. The answer to **which antiemetic is also an antipsychotic** involves several drugs that target the central nervous system's dopamine receptors, which influence both emotional regulation and the body's vomiting reflex.

While drowsiness is a common side effect of prochlorperazine, it is not a medication prescribed for treating insomnia. Primarily an antiemetic and antipsychotic, this phenothiazine derivative works to block dopamine receptors in the brain to control severe nausea, vomiting, and certain mental health conditions.

In 2020, over 600,000 prescriptions were written for the generic version of prochlorperazine, the active ingredient formerly sold under the brand name Compazine. Yet, despite the ongoing use of the generic version, the brand name **Compazine has been discontinued** in the U.S., prompting many to question why a once-prominent medication was removed from the market. The decision stems from significant safety concerns and the emergence of newer, safer alternative drugs.

First approved for medical use in the United States in 1956, the medication known by the brand name Stemetil contains the active ingredient prochlorperazine. So, what class of drug is Stemetil? It belongs to the phenothiazine class, a group of drugs with both antiemetic (anti-sickness) and antipsychotic properties.

The Food and Drug Administration (FDA) issues strong warnings against mixing Central Nervous System (CNS) depressants like prochlorperazine with alcohol due to the high risk of serious and life-threatening side effects. It is critically important to understand why you cannot take prochlorperazine with alcohol to ensure your safety.

While prochlorperazine, the active ingredient in Stemetil, has been a treatment for nausea for decades, its availability has become complex. Contrary to a total withdrawal, the question 'Why has Stemetil been taken off the market?' points to specific product discontinuations, not a complete ban [1.2.1, 1.2.7].

Studies have found that taking multiple medications with anticholinergic properties can significantly increase the risk of cognitive and functional impairment [1.7.1]. This raises the important question: can you take Stemetil with amitriptyline, two drugs with such properties?

In a study of psychiatric inpatients with depressive disorders, nearly 22% received an antidepressant augmented by an antipsychotic. This highlights a common question: can you take prochlorperazine with Lexapro safely? Understanding the interaction is key.

Combining Stemetil (prochlorperazine) and propranolol can cause additive effects in lowering blood pressure, which may increase the risk of dizziness, lightheadedness, and fainting. It is crucial to consult a doctor before taking these medications together to manage potential interactions effectively.

According to prescribing information, hypotension is a documented side effect of prochlorperazine. This guide delves into why prochlorperazine can cause low blood pressure, the mechanism behind it, and what you need to know about managing this potential adverse effect.