Tag: Progesterone withdrawal

In the UK, new prescriptions for progestins (synthetic progesterone) increased from 1.98 per 1,000 person-years-at-risk in 2010 to 6.19 in 2021 [1.9.1]. Understanding **what happens when you stop taking progesterone pills** is crucial, as effects vary based on why you were taking them.

In a study of women who stopped Hormone Replacement Therapy (HRT), about half experienced a recurrence of vasomotor symptoms [1.6.2]. When considering what are the side effects of stopping progesterone, it's important to understand the body's adjustment period to this hormonal shift.

According to a 2023 review, up to 50% of people who discontinue hormone therapy may experience a recurrence of vasomotor symptoms, highlighting the body's reaction to the sudden cessation of hormonal support. This raises the critical question: **what happens to your body if you stop taking progesterone?** The answer depends largely on the reason for treatment, from menopausal therapy to fertility support.

During the first trimester of pregnancy, progesterone levels can be as high as 90 ng/mL [1.6.1]. Understanding how long does it take to get progesterone out of your system is key to managing hormone therapy and its effects.