Tag: Prostaglandin e

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Does PGE Cause Vasoconstriction or Vasodilation? A Pharmacological Review

Oct 11, 2025 •

4 min read

Prostaglandin E1 (PGE1) is a critical medication used to maintain a patent ductus arteriosus in newborns with certain life-threatening heart defects [1.5.3, 1.5.4]. The key question is, does PGE cause vasoconstriction or vasodilation, and how do these complex actions translate to therapeutic use?