Tag: Protein synthesis inhibitor

Puromycin is a powerful antibiotic produced by the bacterium *Streptomyces alboniger*, but its clinical use in humans is prohibited due to high systemic toxicity and poor selectivity. Knowing whether puromycin is toxic to humans is vital for laboratory safety and understanding the serious health hazards associated with exposure.

First isolated from the bacterium *Streptomyces venezuelae* in 1947, chloramphenicol was the first synthetic broad-spectrum antibiotic ever produced in bulk [1.11.1, 1.11.2, 1.11.3]. So, how does chloramphenicol work simple? It functions by halting the production of essential proteins that bacteria need to grow and multiply [1.5.3].

Discovered in 1943, streptomycin was the first antibiotic used to treat tuberculosis, a milestone in infectious disease treatment. Its unique and potent mechanism of action makes it a bactericidal agent, and understanding what best describes the mechanism of action of the antibiotic streptomycin is crucial for its therapeutic use and understanding its effects.

First approved in 1953, the tetracycline class of antibiotics was a major breakthrough in combating a wide range of bacterial infections. If you're wondering what type of antibiotic is tetracycline, the answer is that it's a broad-spectrum, bacteriostatic agent that inhibits protein synthesis within bacteria.

Linezolid was the first member of the oxazolidinone class of antibiotics, approved by the FDA in 2000. This drug, including the injectable form, represents a unique approach to fighting serious, resistant Gram-positive bacterial infections and understanding what is the classification of linezolid injection is key to its clinical use.

Originally approved by the FDA in 2018 for serious infections, omadacycline is an aminomethylcycline antibiotic that represents a significant evolution in its class. It is crucial for clinicians and researchers to understand **what is the mechanism of action of omadacycline**, as it is designed to overcome many of the resistance challenges associated with older tetracyclines.

According to the World Health Organization, clindamycin is an essential medicine for treating a range of bacterial infections. The main function of clindamycin is to combat bacteria by inhibiting their protein synthesis, thereby slowing their growth or killing them.

Aminoglycoside-induced hearing loss has a widely varying incidence, with some studies reporting rates between 2% and 25% [1.8.4]. Understanding how these drugs work is key to their safe use. So, what is the binding site of gentamicin and how does it exert its powerful effects?

According to the U.S. Food and Drug Administration (FDA), the generic name for Synribo is omacetaxine mepesuccinate. This medication was developed to treat certain forms of chronic myeloid leukemia (CML) in patients who had become resistant to or intolerant of other therapies. It is important to note that Synribo has been permanently discontinued and is no longer available in the U.S. market.

Originally isolated from the bacterium *Streptomyces alboniger*, the aminonucleoside antibiotic puromycin is primarily known for its potent ability to inhibit protein synthesis in both prokaryotic and eukaryotic cells, a discovery that has made it an indispensable tool for molecular and cellular biology research.