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Tag: Pseudoephedrine substitutes

Explore our medication guides and pharmacology articles within this category.

What Can Be Substituted for Sudafed? A Guide to Decongestant Alternatives

4 min read
Many people find themselves asking, “What can be substituted for Sudafed?” after learning that the original version with pseudoephedrine is kept behind the pharmacy counter due to regulations. This is an important question, as a 2023 FDA panel found that the commonly available oral decongestant phenylephrine (often sold as Sudafed PE) is not effective at relieving nasal congestion. Understanding the variety of alternatives is key to finding the right, effective relief for your symptoms.