Tag: Psychoactive

First isolated in 2019 by Italian researchers, THCP binds to CB1 receptors with up to 33 times the affinity of Delta-9 THC. This discovery raises the question: Will THCP get you stoned? The answer is a definitive yes, with effects often reported as more intense and longer-lasting than traditional THC.

Cotinine, the primary metabolite of nicotine, can accumulate in the body to levels much higher and for longer durations than nicotine itself. This raises a key question for researchers and health professionals: Does cotinine have psychoactive effects, or is it merely an inert byproduct of nicotine metabolism?

In 2015, an estimated 119 million Americans, or 44.5% of the population aged 12 or older, used prescription psychotropic drugs [1.4.1]. The answer to 'What are brain drugs called?' is complex, encompassing several classes of medications that affect brain chemistry.

Kratom contains over 40 alkaloids, with mitragynine and 7-hydroxymitragynine being the most active [1.5.6]. The question of whether **is kratom serotonin or dopaminergic** is complex, as research shows it interacts with multiple neurotransmitter systems, not just one [1.2.2].

The cannabis plant contains over 60 natural cannabinoids, but it is primarily one chemical, tetrahydrocannabinol (THC), that gets you stoned by interacting with your body's endocannabinoid system. Understanding these complex interactions is crucial for navigating the effects of cannabis and other psychoactive substances.

Reports from clinical trials dating back to 2005 indicated that pregabalin produced acute euphoric effects in an unusually high percentage of individuals, leading to its classification as a controlled substance. The question, **is pregabalin psychoactive**, is thus answered with a definitive 'yes,' which is a key reason for its regulatory control.

According to the Centers for Disease Control and Prevention, CBD is not impairing, meaning it does not cause a "high". While both cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC) are cannabinoids derived from the cannabis plant, their distinct chemical structures lead to vastly different effects on the brain.

Did you know that the cannabis plant produces THCa, a non-psychoactive compound, rather than Delta 9 THC in its raw form? For those asking, “Is THCa as strong as Delta 9?”, the simple answer depends entirely on whether heat is applied, a process that dramatically alters its effects and potency.

Contrary to some online rumors, shilajit does not contain any psychoactive compounds and will not make you feel high. This potent Ayurvedic compound is instead known for its adaptogenic properties and its potential to enhance physical and mental energy in a more subtle, supportive way.

Evidence suggests mescaline, the primary psychoactive alkaloid found in cacti like peyote, has been used in ceremonial contexts for over 5,700 years. This powerful hallucinogen is the answer to the question, "What drug do you get from cactus?", and it originates from several species native to the Americas.