Tag: Ptp1b inhibitor

Despite completing early-stage clinical trials for conditions like diabetes and obesity, the experimental drug trodusquemine remains unavailable for human medical use. Its availability is restricted exclusively to laboratory research purposes, preventing its acquisition for personal health treatment.

Trodusquemine is an investigational drug not approved for human use by the FDA, meaning it has no standard consumer price [1.3.1]. The key question remains: how much does trodusquemine cost in the USA for research purposes?

In pre-clinical studies, a single dose of trodusquemine led to a 20% reduction in body weight in mice on a high-fat diet [1.3.9]. This article explores the question: What are the benefits of trodusquemine, an investigational drug with a unique mechanism of action?

As of late 2025, Trodusquemine is not approved by the U.S. Food and Drug Administration (FDA) for human use and is not commercially available in the United States. The compound remains an investigational drug, available only for research purposes through commercial suppliers.

Over the past two decades, the compound trodusquemine (MSI-1436) has been passed between multiple companies, each exploring its potential for different conditions from obesity to muscular dystrophy. The tumultuous history of who is developing trodusquemine highlights the high-stakes and often volatile nature of pharmacological research and development.

Trodusquemine (also known as MSI-1436) can be purchased from commercial suppliers for research purposes, but it is not available for human use in the USA [1.3.1]. This investigational drug has not been approved by any regulatory agency for public sale or prescription [1.2.2].

Initial Phase I clinical trials for Trodusquemine showed good tolerability and promising results for metabolic conditions, but several planned Phase II trials were abruptly halted due to the original developer's financial collapse. This financial failure, not safety or efficacy issues, largely explains what happened to Trodusquemine's progress as a potential commercial drug.

Trodusquemine is not currently approved for human use and therefore does not have a commercial price for patients. Its cost is associated solely with its status as a research chemical, with prices varying significantly between suppliers and depending on the quantity purchased.

Trodusquemine (also known as MSI-1436) is a naturally occurring aminosterol originally discovered in the dogfish shark. This article explains how trodusquemine is administered within the context of its use in clinical research, as it is not approved for public use.

Trodusquemine (also known as MSI-1436) is an aminosterol first isolated from the dogfish shark, *Squalus acanthias*, over two decades ago. Despite its interesting biological properties, the definitive answer to, "Can I buy trodusquemine?" is no, as it is an unapproved, experimental compound unavailable for public purchase.