What drugs cause purple glove syndrome and how to prevent it?
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4 min read
Intravenous (IV) administration of phenytoin, an anti-seizure medication, is the overwhelmingly primary cause of a rare and potentially serious adverse reaction known as purple glove syndrome (PGS). Affecting anywhere from 1.7% to 5.9% of patients receiving IV phenytoin, this condition can cause severe pain, swelling, and discoloration of the hand and forearm.
