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Tag: Quinolones

Explore our medication guides and pharmacology articles within this category.

What is the mechanism of action of quinolones?

4 min read
Over five decades ago, the first quinolone, nalidixic acid, was discovered as a byproduct during synthesis. Its legacy continues with modern fluoroquinolones, which work by a precise mechanism of action of quinolones that targets essential bacterial enzymes to halt DNA replication and trigger cell death.

What are quinolones? A Comprehensive Guide to This Antibiotic Class

5 min read
In 2014, approximately 22 million patients in the U.S. received a prescription for an oral fluoroquinolone antibiotic [1.5.1]. So, **what are quinolones**? They are a class of broad-spectrum antibiotics used to treat a wide variety of bacterial infections by inhibiting bacterial DNA synthesis [1.2.1, 1.4.1].

How Do Quinolones Work? The Mechanism Behind These Potent Antibiotics

4 min read
First discovered in the 1960s, quinolone antibiotics function as potent bactericidal agents that interfere with bacterial DNA replication, ultimately leading to cell death. This crucial mechanism of action involves the inhibition of specific enzymes essential for bacterial survival, which is why understanding how do quinolones work is so important for effective treatment.