Tag: Rauwolscine

Despite being structurally similar, rauwolscine (alpha-yohimbine) and yohimbine are not the same molecule. They are actually stereoisomers, meaning they share the same chemical formula ($C_{21}H_{26}N_2O_3$) but possess a different three-dimensional arrangement that affects their potency and how they interact with the body's receptors.

As an isomer of yohimbine, rauwolscine acts primarily as an alpha-2 adrenergic receptor antagonist, meaning it blocks receptors that normally inhibit the release of norepinephrine. This action stimulates the nervous system and is the basis for its use in supplements marketed for fat loss and energy enhancement, though human clinical evidence is limited.