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Tag: Re titration

Explore our medication guides and pharmacology articles within this category.

Medications,Pharmacology: What is the 48 hour rule for clozapine?

4 min read
According to regulatory guidelines, if a patient misses their clozapine dose for more than 48 hours, they must be treated as if starting the medication for the first time. This safety protocol, known as the **48 hour rule for clozapine**, is a crucial pharmacological standard designed to prevent severe adverse effects associated with abruptly restarting this powerful antipsychotic medication.