Why is Penthrox not available in the USA? A look into its complex regulatory history
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4 min read
While the fast-acting pain relief inhaler Penthrox, known informally as the “green whistle,” is a common sight in emergency and trauma settings across Australia and Europe, the medication is not available for civilian use in the USA. Its absence is rooted in a complicated history with its active ingredient, methoxyflurane, and a formal safety determination made by the US Food and Drug Administration (FDA) nearly two decades ago.
