Tag: Rems program

Clozapine-induced agranulocytosis, a severe drop in white blood cells, occurs in about 0.8% to 1.2% of patients [1.3.2, 1.5.6]. This risk necessitates a strict monitoring schedule. So, **how often should I check my CBC with clozapine?** The frequency changes over the course of treatment.

The Food and Drug Administration (FDA) first approved the brand-name medication Letairis in 2007 for the treatment of pulmonary arterial hypertension (PAH). Since the patent expired, the active ingredient is now available as a generic version, making the generic for Letairis, which is ambrisentan, a more affordable option for many patients.

An estimated 192,000 people globally had pulmonary arterial hypertension (PAH) in 2021 [1.9.1]. For many, a key question is, **what is bosentan 62.5 mg used for?** This medication is a cornerstone therapy for managing this serious condition by improving exercise ability and slowing disease progression [1.2.1, 1.2.2].