Tag: Renal effects

Millions of Americans take nonsteroidal anti-inflammatory drugs (NSAIDs) like Aleve (naproxen sodium) for pain, but many are unaware of its potential impact on circulation, prompting the question, 'Does Aleve restrict blood flow?'. This effect is particularly relevant for those with pre-existing heart and kidney conditions, as the drug's mechanism can indeed lead to some blood vessel constriction.

Studies show that when ciclopirox is applied topically, systemic absorption is minimal, with typically less than 5% of the dose being absorbed [1.2.1, 1.2.3]. This article explores the question: **does ciclopirox affect the kidneys** given its primary elimination route?

While not a typical side effect of normal use, a rare case report detailed severe hypomagnesemia after an ibuprofen overdose in a young child. This has prompted questions for many: can ibuprofen cause magnesium deficiency, and under what circumstances should you be concerned? (47 words)