Tag: Renal safety

Studies show that using atypical antipsychotics can increase the risk of acute kidney injury (AKI) by over 70% in older adults [1.4.1]. This guide addresses the critical question: What is the safest antipsychotic for kidneys?

While older HIV treatments containing tenofovir disoproxil fumarate (TDF) were more commonly associated with kidney toxicity, **Biktarvy** uses a newer, safer form of tenofovir that significantly reduces this risk. However, like many medications, it is not without risk, and instances of new or worsening kidney problems have been reported.

According to the FDA, long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) like naproxen is associated with an increased risk of heart attack and stroke. This risk is compounded when patients are also managing hypertension with medications such as amlodipine, raising critical questions about whether you can take naproxen with amLODIPine.

Clinical trials, such as the DISCOVER trial, have shown that Descovy is associated with improved renal biomarkers compared to Truvada. This critical finding leads many to ask: is Descovy better for kidneys than Truvada? The answer lies in the different versions of the tenofovir drug they contain and individual patient health factors.

Yes, older formulations of the medication tenofovir, specifically tenofovir disoproxil fumarate (TDF), have been definitively linked to an increased risk of kidney problems, from a mild, predictable decline in function to more severe conditions like Fanconi syndrome. The development of a newer prodrug, tenofovir alafenamide (TAF), aimed to address these concerns by significantly reducing the drug's plasma concentration.

According to studies, vancomycin can cause nephrotoxicity in up to 10% of patients, particularly with high-dose or prolonged treatment. For healthcare providers and patients alike, understanding how to avoid vancomycin nephrotoxicity is crucial to ensure both therapeutic efficacy and patient safety.

Benign Prostatic Hyperplasia (BPH) affects about 50% of men over 50 and 90% of men by their 80s, with finasteride being a primary treatment. This widespread use raises a critical question for long-term users: **is finasteride hard on the kidneys?**