Tag: Resiniferatoxin

Explore our medication guides and pharmacology articles within this category.

What drugs activate TRPV1?: A Guide to Agonists and Their Therapeutic Uses

Oct 13, 2025 •

5 min read

Transient receptor potential vanilloid 1 (TRPV1) is a non-selective cation channel best known as the receptor for capsaicin, the pungent compound in chili peppers. Its activation by various chemical and physical stimuli triggers a burning sensation and is crucial for pain signaling. Understanding what drugs activate TRPV1 is key to developing novel analgesics and other therapeutics.

What is a TRPV1 Agonist Drug? A Comprehensive Guide to its Mechanism and Uses

Oct 13, 2025 •

5 min read

The active component in chili peppers, capsaicin, is the most well-known example of a TRPV1 agonist drug. These medications work by activating the Transient Receptor Potential Vanilloid 1 (TRPV1) receptor, eventually creating a powerful and long-lasting analgesic effect for chronic pain management.