What Drugs Are Restrictively Cleared and Why It Matters in Pharmacology
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5 min read
Approximately 97% of the anticoagulant warfarin is bound to plasma proteins, making it a classic example of what drugs are restrictively cleared. This pharmacokinetic concept is essential for understanding how certain medications are eliminated from the body and why their clearance is highly dependent on factors like plasma protein levels and intrinsic metabolic capacity.
