Unlocking the Code: What is the mechanism of action of bexarotene?
•
4 min read
In clinical trials for advanced-stage cutaneous T-cell lymphoma (CTCL), bexarotene demonstrated an overall response rate of 45-55% in patients refractory to previous systemic therapies. Understanding **what is the mechanism of action of bexarotene** involves exploring its role as a selective retinoid X receptor (RXR) agonist and its profound influence on gene transcription.