Is physostigmine reversible or irreversible? An in-depth pharmacological guide
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4 min read
Pharmacologically, physostigmine is a reversible cholinesterase inhibitor, a critical distinction from the highly toxic irreversible organophosphates used in nerve agents and pesticides. Derived from the Calabar bean, this compound temporarily blocks the enzyme that breaks down acetylcholine, impacting both the central and peripheral nervous systems. This reversible action defines its therapeutic application, primarily as an antidote in toxicology.
