Tag: Ribosomes

While many antibiotics that inhibit bacterial protein synthesis are only bacteriostatic, simply halting growth, aminoglycosides have a uniquely lethal mechanism. This article explores the cascade of synergistic and irreversible events that explains **why are aminoglycosides bactericidal and not bacteriostatic**.

While macrolide antibiotics have been in clinical use for over seven decades, our understanding of precisely **how do macrolides act** has evolved significantly from the initial theories. These bacteriostatic drugs target a crucial component of bacterial machinery to disrupt protein production, thereby halting bacterial growth and proliferation.

Unlike many other protein synthesis inhibitors that are bacteriostatic, aminoglycosides are rapidly bactericidal. This unique feature is central to understanding how do aminoglycosides work and their clinical applications against serious bacterial infections.