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Tag: Risk assessment

Explore our medication guides and pharmacology articles within this category.

What Are the 4 Types of Toxicity?: A Guide to Medications and Pharmacology

3 min read
It is estimated that drug toxicity contributes to the attrition of approximately one-third of drug candidates during development. Understanding the distinct types of toxicity is therefore crucial in pharmacology and medicine. This article breaks down **what are the 4 types of toxicity**, detailing how exposure duration and dosage define their effects on the body.

Which drug is the least damaging?: A pharmacological guide to assessing risk

5 min read
According to a 2017 Global Drug Survey, psilocybin mushrooms had the lowest rate of hospital admissions among recreational drugs studied, highlighting the complexity in determining which drug is the least damaging, as risk depends on various factors beyond legality. There is no single drug without any potential for harm; instead, risk is a multi-faceted assessment determined by a drug’s mechanism, dose, and an individual’s health.

How safe is Penthrox? Analyzing the Inhaled Analgesic's Risk Profile

3 min read
According to a 2024 study, 90% of patients reported an overall good-to-excellent experience with Penthrox for pain relief, highlighting its favorable tolerability. However, a comprehensive understanding of its safety is crucial for healthcare providers and patients alike, making the question **How safe is Penthrox?** a vital one.

Can I have an operation if on antibiotics? A guide to surgery and infection management

4 min read
According to the CDC, surgical site infections (SSIs) account for a significant percentage of healthcare-associated infections, underscoring the critical importance of proper infection management during surgery. When preparing for a procedure, it is crucial to understand if you can have an operation if on antibiotics and what factors will influence your care plan.

Decoding the Doctor's Dilemma: Why do doctors not want to prescribe progesterone?

5 min read
The 2002 Women's Health Initiative (WHI) study, which linked hormone replacement therapy to increased health risks, profoundly shaped medical practice and is a primary reason for hesitation when patients ask, "Why do doctors not want to prescribe progesterone?". However, the reality is far more nuanced, encompassing a variety of factors from individual patient risk profiles to ongoing scientific debates about hormone types and administration.

Which is safer, doxycycline or ciprofloxacin? A comparative analysis of antibiotic risks

5 min read
The U.S. FDA has issued multiple safety warnings regarding the potential for serious, disabling side effects from fluoroquinolone antibiotics like ciprofloxacin. This critical information prompts a closer look at the question: Which is safer, doxycycline or ciprofloxacin? The answer depends heavily on the patient's specific infection, health profile, and a careful assessment of risks associated with each medication.

What is a subchronic toxicity? Understanding Repeated Dose Safety Studies

3 min read
According to regulatory guidelines, many subchronic toxicity studies in rodents typically last for 90 days. Understanding what is a subchronic toxicity and its purpose is fundamental for evaluating the potential health risks associated with repeated, moderate-term exposure to a substance, such as a new drug candidate or chemical.

Can You Stay on Amitriptyline for Life? Long-Term Safety, Risks, and Management

6 min read
While traditionally used for depression, amitriptyline is also a go-to medication for managing chronic pain, migraine, and insomnia, often at much lower doses. The possibility of long-term treatment raises a critical question for many patients: **can you stay on amitriptyline for life?** A definitive answer hinges on careful consideration of sustained benefits, potential long-term risks, and consistent medical oversight.