Tag: Rna interference

Explore our medication guides and pharmacology articles within this category.

What is the new injection for hypertension?: An advanced look at zilebesiran

Oct 9, 2025 •

4 min read

Nearly half of American adults with high blood pressure do not have it under control with traditional daily medication. A promising development is zilebesiran, a new injection for hypertension currently in advanced clinical trials, which could offer patients sustained blood pressure control with just a twice-yearly dose.

Is ONPATTRO a gene therapy? Unpacking RNA Interference vs. Genetic Modification

Oct 8, 2025 •

4 min read

ONPATTRO (patisiran) was the first-ever small interfering RNA (siRNA) therapeutic approved by the U.S. Food and Drug Administration (FDA) in 2018 for treating a genetic disease. This groundbreaking treatment, which works by "silencing" a gene, has raised a crucial question in the field of genetic medicine: is ONPATTRO a gene therapy?