Tag: Rosiglitazone

Yes, Avandia (rosiglitazone) was made commercially unavailable in the United States in January 2024, marking the end of its long and controversial market presence. The manufacturer's decision followed a dramatic decrease in the drug's use over a decade due to significant cardiovascular safety concerns and regulatory actions.

According to the CDC, over 38 million Americans have diabetes, and about 90–95% of them have type 2 diabetes. A TZD medication, short for thiazolidinedione, is a class of oral drugs prescribed to manage this condition by improving the body's response to insulin.

Approximately 5-15% of patients taking thiazolidinediones experience some form of fluid retention or edema. Understanding **which diabetes medications cause edema?** is crucial for managing this common side effect and preventing potential complications, such as exacerbating pre-existing heart failure.

As of early 2024, the manufacturer of Avandia (rosiglitazone), Woodward Pharma Services, has stated that the controversial diabetes drug is no longer available in the United States. Its availability has been severely impacted by regulatory actions and safety concerns that arose over two decades, making the question of 'Is Avandia available in the US?' a complex one with a definitive modern answer.

In 2010, the diabetes drug Avandia was effectively banned in Europe and severely restricted in the U.S. due to mounting evidence linking it to an increased risk of serious cardiovascular events, including heart attacks and heart failure. This was the culmination of years of controversy and conflicting scientific findings regarding the safety of the once-popular medication.