What is the best pain reliever to take with prednisone?
•
4 min read
According to healthcare professionals, acetaminophen (Tylenol) is generally considered the safest over-the-counter pain reliever to take alongside prednisone. Combining prednisone with other common pain relievers, particularly NSAIDs like ibuprofen and naproxen, can significantly increase the risk of adverse side effects.