Tag: San pedro cactus

Evidence suggests the ceremonial use of mescaline, a naturally occurring alkaloid, dates back over 5,700 years in some indigenous cultures. This primary compound answers the question, "What is a cactus born psychedelic drug?," with the peyote cactus and San Pedro being its most famous botanical sources.

Archaeological evidence suggests that humans have used psychoactive substances for millennia, with some of the earliest examples dating back over 8,000 years. Pinpointing exactly what is the oldest psychedelic drug is a complex task, with several powerful contenders vying for the title based on ancient plant remains, artwork, and historical texts.