Tag: Sedation failure

Studies show that up to one in three critically ill patients receiving prolonged analgosedation may experience difficult sedation [1.4.1]. This clinical challenge raises the question: **Why are some patients difficult to sedate**, requiring higher or different medication doses to achieve a safe effect?

While sedation is highly effective for the vast majority of patients, one study identified a failure rate of 0.10% for standard sedation procedures in routine GI endoscopy, even among higher-risk patients. In the rare but serious event that sedation doesn't work, it is crucial for medical professionals to have a clear understanding of the underlying causes, risks, and necessary responsive strategies to manage the situation and ensure patient safety.