Tag: Selectivity

Up to 90% of drug candidates fail during development, largely due to issues with efficacy and safety. Understanding what is the key aspect of drug design—achieving a specific and effective interaction with a biological target—is crucial for improving these statistics and advancing new therapeutic treatments.

In pharmacology, the half-maximal inhibitory concentration (IC50) is a critical measure for assessing a drug's potency, representing the concentration required to inhibit a biological process by 50%. This value is fundamental to drug discovery and understanding inhibitory effectiveness. So, is high or low IC50 better for a medication?