Tag: Serotonergic

Kratom contains over 40 alkaloids, with mitragynine and 7-hydroxymitragynine being the most active [1.5.6]. The question of whether **is kratom serotonin or dopaminergic** is complex, as research shows it interacts with multiple neurotransmitter systems, not just one [1.2.2].

Affecting over 280 million people globally, major depressive disorder often requires medication, with many options available. A unique type of treatment is what is a NaSSA medication, which stands for Noradrenergic and Specific Serotonergic Antidepressant. Unlike more common selective serotonin reuptake inhibitors (SSRIs), NaSSAs employ a distinct dual-action mechanism to help regulate mood.

Although the incidence is low, linezolid, an antibiotic used for serious bacterial infections, has been implicated in causing serotonin syndrome due to its weak monoamine oxidase inhibitor (MAOI) properties, especially when combined with other serotonergic agents.