Can Tramadol Cause Serotonin Syndrome? Understanding the Risks
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4 min read
According to a review of the FDA's Adverse Event Reporting System, serotonin syndrome accounted for 3% of all reported tramadol cases between 1997 and 2017. This confirms that yes, tramadol can cause serotonin syndrome, a potentially dangerous condition resulting from excessive serotonin levels in the brain. The risk is particularly heightened by drug interactions and higher doses.