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Tag: Siadh

Explore our medication guides and pharmacology articles within this category.

Investigating the Link: Can Buspirone Cause Hyponatremia?

4 min read
Case reports indicate that while uncommon, a link between buspirone use and hyponatremia is possible, sometimes occurring with other serotonergic drugs [1.2.1, 1.3.2]. So, can buspirone cause hyponatremia? This article reviews the evidence, potential mechanisms, and clinical considerations for this adverse effect.

Can Bupropion Cause Low Sodium Levels? An Overview of Hyponatremia Risk

4 min read
While bupropion is often cited as having a lower risk of hyponatremia compared to other antidepressants, several case reports confirm that **bupropion can cause low sodium levels**, particularly in susceptible individuals. This potentially serious side effect, if not identified and managed promptly, can lead to significant health complications.

Which antidepressants are most likely to cause hyponatremia?

3 min read
The incidence of hyponatremia with selective serotonin reuptake inhibitors (SSRIs) can range from 0.5% to 32% [1.5.1]. Understanding which antidepressants are most likely to cause hyponatremia, a condition of low sodium in the blood, is crucial for patient safety.

When to use demeclocycline?: Unpacking its specialized indications

4 min read
While historically used as a tetracycline antibiotic, demeclocycline's primary therapeutic role has shifted, and it is now more commonly recognized for its off-label use in managing chronic hyponatremia caused by the Syndrome of Inappropriate Antidiuretic Hormone (SIADH). Understanding when to use demeclocycline involves differentiating its diminishing antibacterial use from its specialized endocrine application.

What Medications Block ADH? A Guide to Antidiuretic Hormone Antagonists

4 min read
According to research, hyponatremia, a condition characterized by low serum sodium, affects 4-15% of hospitalized patients and is often the most frequent electrolyte disorder. In many of these cases, excess antidiuretic hormone (ADH) is a contributing factor, necessitating the use of medications that block ADH, known as vasopressin receptor antagonists or 'vaptans'.

Which of the following medications is most likely to cause hyponatremia?

5 min read
Medication-induced hyponatremia is a common electrolyte imbalance, accounting for a significant number of hospitalizations, with one study noting that thiazide diuretics alone contribute to up to 25% of cases. Understanding which of the following medications is most likely to cause hyponatremia is crucial for patient safety, especially among vulnerable populations like the elderly. This guide explores the most frequent culprits and their underlying mechanisms.

What is the purpose of demeclocycline? Understanding its dual role

3 min read
Demeclocycline is a unique medication, known for its dual-purpose role as a broad-spectrum tetracycline antibiotic and, notably, as an off-label treatment for a condition called the syndrome of inappropriate antidiuretic hormone secretion (SIADH). While its use for infections has largely declined, its pharmacological side effect is leveraged therapeutically.

What is the drug Declo used for?: Clarifying the Medication Declomycin

4 min read
The brand name Declomycin, often associated with the query 'What is the drug Declo used for?', refers to the medication demeclocycline, a tetracycline antibiotic that has been discontinued. This medication was primarily used to treat various bacterial infections, but it also had a unique application in managing the Syndrome of Inappropriate Antidiuretic Hormone secretion (SIADH).