Tag: Sick day rule

Clinical guidelines and patient information confirm that pausing methotrexate is often necessary when signs of an infection appear. **Should you take methotrexate if you're unwell?** The immediate and safest course of action is to temporarily hold your weekly dose and contact your healthcare provider for specific advice based on your symptoms.

Approximately 30-45% of patients taking methotrexate for inflammatory conditions may experience side effects, necessitating careful management during illness. This is why every patient needs to understand **what is the sick day rule for methotrexate** and how to follow it correctly for their health and safety.