Tag: Sickle cell disease

Hydroxyurea is a vital medication for managing conditions like sickle cell disease, with usage rates in some pediatric programs exceeding 90% [1.10.1]. But a common question is, *does hydroxyurea affect sleep?* The answer is complex, involving both direct and indirect effects on sleep patterns.

Consistency is the single most important factor when it comes to the timing of hydroxyurea, a medication used to treat certain cancers and sickle cell disease. While there is no universal "best" time, selecting a consistent schedule is crucial for maintaining stable drug levels in your body.

In December 2023, the U.S. Food and Drug Administration (FDA) approved the world's first CRISPR-based therapy, Casgevy, marking a historic shift in treating genetic blood disorders. This groundbreaking approach directly modifies a patient's own cells, which is central to understanding what is the active ingredient in Casgevy.

According to SingleCare, the average retail price for a one-month supply of generic hydroxyurea can be over $80 without insurance, but discount cards can drastically reduce this figure to under $20. How much is hydroxyurea in the USA depends heavily on whether you use the generic or a brand-name version and your insurance status.

In a landmark decision in late 2023, the U.S. FDA approved Casgevy, the first treatment utilizing CRISPR technology to receive authorization. Understanding **how does casgevy gene therapy work** involves a look at its process of gene editing to enable a patient's body to produce healthy blood cells.