Tag: Skin discoloration

Drug-induced pigmentation is estimated to account for up to 20% of all cases of acquired hyperpigmentation [1.3.3, 1.3.5, 1.4.4]. If you've ever asked, 'What drug changes your skin color?', the answer involves a wide range of medications that can alter skin tone through various mechanisms [1.2.1].

According to research, one of the most common and distinctive adverse effects of rifampin is the harmless discoloration of body fluids, which can include the skin, sweat, and tears. Understanding **what are the side effects of rifampin on the skin** is crucial for patients, as these can range from this expected change to rare but life-threatening allergic reactions. This guide details both the common and serious dermatological impacts of the medication.

Latanoprost, a prostaglandin F2α analogue often prescribed for glaucoma, is known to cause a number of cutaneous side effects, with eyelid skin darkening and eyelash changes being among the most common. While many of these effects are cosmetic and reversible upon discontinuation, some can be permanent. Understanding the full spectrum of **what are the side effects of latanoprost on the skin** is essential for patient counseling and management.

According to reports, millions of Americans have used kratom, a substance derived from the *Mitragyna speciosa* tree. A rare but increasingly recognized cutaneous side effect associated with chronic, long-term kratom use is hyperpigmentation, a skin discoloration that can manifest as brown, gray, or blue-gray patches. These effects, documented in numerous case reports, highlight a potentially serious dermatological consequence of the unregulated substance.

While minoxidil is a well-established hair loss treatment, clinical guidelines note that pigmentary changes are an uncommon adverse effect. These complications can include both hyperpigmentation (skin darkening) and hypopigmentation (skin lightening), highlighting the need for awareness regarding all potential side effects.