Tag: Smon

Over 10,000 people were affected by subacute myelo-optic neuropathy (SMON) in Japan between 1957 and 1970, with the resulting investigation conclusively linking the disease to the oral administration of enteroquinol. This connection led to the drug's global ban for oral use and a re-evaluation of drug safety standards worldwide.

First synthesized in 1899, the medication known as **clioquinol** has a complex history and several aliases. Its generic name, iodochlorhydroxyquin, was once widely used for treating various infections but is now known for its controversial past, leading to its restriction primarily to specific topical applications.