Tag: Soft tissue healing

Studies show that cyclooxygenase-2 (COX-2), the enzyme targeted by Celebrex, is rapidly upregulated after an injury to mediate inflammation and healing. But does Celebrex interfere with healing? The answer is complex, with evidence pointing to potential delays, particularly in bone and certain soft tissues.

Research indicates that high doses of aspirin, a common nonsteroidal anti-inflammatory drug (NSAID), can indeed impede the healing process by disrupting the crucial initial phases of inflammation and tissue repair. While low doses are less impactful and sometimes used to prevent blood clots, its effects vary based on tissue type, dosage, and whether the wound is acute or chronic.