Tag: Ssri safety

According to a 2025 analysis published in *PLOS ONE*, overall antidepressant use in individuals with depression showed no statistically significant association with all-cause mortality after controlling for confounding factors, though initial unadjusted rates appeared higher. However, the question "Do antidepressants affect lifespan?" remains complex, with conflicting studies and a critical need to differentiate between the effects of medication and the profound impact of the underlying illness itself.

According to the National Center for Health Statistics, millions of Americans have been prescribed sertraline, making it one of the most widely used antidepressants. However, despite its widespread use, it is crucial for both patients and healthcare providers to understand **who shouldn't take sertraline** due to significant risks associated with certain medications and pre-existing health conditions.