Tag: Steroid sparing agents

In February 2023, the FDA approved Kevzara (sarilumab), making it the first and only biologic injection for polymyalgia rheumatica (PMR) in adults who have not responded well to or cannot tolerate corticosteroids. While oral corticosteroids are the standard first-line treatment, injectable options like Kevzara provide a valuable alternative for challenging cases.

Prednisone treatment for Polymyalgia Rheumatica (PMR) typically lasts one to two years, though many individuals require treatment for longer periods. The duration and tapering schedule are highly individualized and depend on symptom control and relapse prevention.

While dexamethasone is a potent and effective corticosteroid, a 2022 study on children with croup showed similar hospital resource utilization between those receiving dexamethasone and those given prednisone or prednisolone, suggesting other options can be viable for specific conditions. For those exploring alternatives, understanding your options is the critical first step in determining **what can I take instead of dexamethasone?**

Studies suggest that between 12.2% and 18.1% of people who receive oral glucocorticoids like prednisone become long-term users [1.5.2]. For these individuals, the critical question becomes: **what can you take long term instead of prednisone?**