Tag: Stopping methotrexate

While the drug methotrexate is mostly cleared from the body of a non-pregnant adult within one week, the clinical effects can take longer to wear off. For patients wondering **how long does it take to feel better after stopping methotrexate?**, the answer depends on whether you are recovering from temporary side effects or navigating the re-emergence of your underlying condition.

In a study of rheumatoid arthritis (RA) patients, discontinuing methotrexate for four weeks increased the risk of a disease flare to over 20% [1.4.2]. Understanding what are the side effects of stopping methotrexate is crucial for anyone considering altering their treatment plan.