Tag: Stopping semaglutide

Semaglutide has a half-life of approximately one week, which is a key factor in determining how long does semaglutide stay in your system once you stop? [1.3.1, 1.3.3]. It can take four to five weeks after the final dose for the drug to be completely cleared from the body [1.2.1, 1.8.1].

Clinical trial data shows that participants who stop taking semaglutide often regain approximately two-thirds of their lost weight within a year. Understanding **when to stop semaglutide** and preparing for the biological and lifestyle changes that follow is crucial for maintaining long-term health benefits.

One year after stopping once-weekly semaglutide, participants in a clinical trial extension regained two-thirds of their prior weight loss [1.3.2]. This statistic highlights a crucial question for users: **how long should I stay on compounded semaglutide** to maintain results?