Tag: Suicidality

In 2004, the U.S. Food and Drug Administration (FDA) mandated that all antidepressant medications, including Zoloft (sertraline), carry a prominent "black box" warning regarding an increased risk of suicidal thoughts and behaviors. This serious caution is primarily directed at children, adolescents, and young adults under the age of 25.

According to the FDA, antidepressants like Zoloft carry a boxed warning for increased suicidal thoughts and behaviors in young adults under 25, especially at the start of treatment or after a dosage change. Understanding what is the dark side of Zoloft, including this serious risk and other potential adverse effects, is critical for both patients and healthcare providers.

Antidepressants increased the risk of suicidal thinking and behavior in short-term studies in children, adolescents, and young adults. So, what is the black box warning on desipramine and what does it mean for patients?