Tag: Supportive care

Nonsteroidal anti-inflammatory drugs (NSAIDs) are implicated in nearly 25% of all adverse drug reactions [1.4.7]. When it comes to overdose, many ask: **What is the antidote for NSAIDs?** The direct answer is that one does not exist; treatment relies entirely on supportive care [1.2.2, 1.2.5].

In cases of overdose, there is no specific antidote for pregabalin, making symptomatic and supportive care the cornerstone of management. While isolated pregabalin overdoses often cause only mild symptoms, severe toxicity can occur, especially with co-ingestion of other central nervous system depressants like opioids.

Despite being one of the most widely consumed psychoactive substances globally, there is no single, specific antidote or reversal agent for caffeine intoxication. Instead of a quick fix, managing the effects of too much caffeine relies on the body's natural metabolism and supportive care.

As a potent chemical warfare agent, sulphur mustard causes devastating burns and long-term health problems; however, despite its history of use dating back to World War I, no specific antidote exists to reverse its toxic effects. Instead, emergency management focuses on rapid decontamination and aggressive supportive care to mitigate the damage caused by exposure.

According to the CDC, patients who survive the initial 24 hours of acute tetrodotoxin intoxication typically recover without residual deficits. While there is no specific antidote, a full recovery is possible, highlighting the critical importance of prompt and aggressive supportive medical intervention to survive tetrodotoxin poisoning.

Tetrodotoxin (TTX) is a potent neurotoxin found in pufferfish and other marine life that works by blocking voltage-gated sodium channels. However, the question, 'Is tetrodotoxin reversible?', requires a closer look at the difference between its action at the cellular level and the management of a severe human poisoning case.

Chandipura virus (CHPV) is an emerging pathogen with a high case-fatality ratio, ranging from 56-75%, particularly in children [1.2.1, 1.5.3]. Given its severity, the crucial question is: what drugs are used to treat Chandipura virus?

In 2023, there were 10,870 drug overdose deaths involving benzodiazepines like alprazolam [1.6.3]. While overdoses are a serious concern, many wonder: **what is the antidote for alprazolam?** The answer lies in a specific medication, though its use is complex [1.2.5].

Approximately half of all cancer patients receive chemotherapy, with dexamethasone often prescribed to manage common side effects like delayed nausea and vomiting. If you have forgotten to take your dexamethasone after chemo, it is important to know the appropriate course of action to ensure your medication's effectiveness and your overall comfort.

Corticosteroids have been a standard part of anti-nausea and anti-inflammatory regimens for chemotherapy for decades. But with evolving treatment protocols and new medications, the question remains: Are steroids necessary for chemotherapy in every case?