Tag: Syphilis treatment

While overall STI rates have shown some decline, congenital syphilis cases in the U.S. increased for the 12th consecutive year in 2024. So, what is the main drug used to treat syphilis? For decades, the answer has remained injectable Penicillin G.

In 2023, the United States reported 209,253 cases of syphilis, the highest number since 1950. Amid rising cases, a key question for many is: **does doxycycline treat syphilis?** This antibiotic serves as a critical alternative to standard penicillin therapy.

Amidst a national shortage of Bicillin L-A, the FDA has permitted the temporary importation of Extencilline to treat conditions like syphilis [1.2.1, 1.7.3]. What is the difference between Bicillin L-A and Extencilline? While both share the same core antibiotic, key distinctions exist in their formulation, preparation, and administration.

Syphilis cases have been on the rise globally in recent years. In the context of this public health concern, the question 'Can moxifloxacin cure syphilis?' is a critical one for many patients seeking reliable information. The definitive answer, according to medical research and major health organizations, is no.

Fear of needle pain can be a significant factor in medical avoidance [1.7.4]. So, exactly how painful is a penicillin injection, a shot known for its discomfort? The answer lies in the medicine's unique physical properties and the nature of the injection itself [1.2.1, 1.2.2].

Following a U.S. drug shortage beginning in 2023, the FDA granted temporary authorization for the importation of **what is extencilline**, a long-acting penicillin G benzathine used to treat syphilis and other serious bacterial infections. Marketed as Extencilline in other countries, it serves as a critical alternative during supply disruptions of Bicillin L-A®.

Globally, millions of doses of benzathine penicillin are used annually to treat bacterial infections; it's the first-line treatment for syphilis and for preventing rheumatic fever. So, what is benzathine for and how does this essential long-acting antibiotic work?

A long-acting injectable antibiotic containing benzathine benzylpenicillin, Zalpen is a medication primarily used to combat infections caused by highly susceptible bacteria, notably as a standard treatment for syphilis and for preventing rheumatic fever.