Does lidocaine have an euphoric effect? Understanding the risks of systemic toxicity
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4 min read
Reports of lidocaine-related euphoria are extremely rare, primarily occurring in cases of central nervous system (CNS) toxicity. This anesthetic is not considered addictive and lacks the rewarding properties associated with drugs of abuse. The fleeting "high" described in some anecdotal cases is a serious sign of overdose, not a desirable recreational effect.