Understanding the Pharmacological Reasons: Why Does Levofloxacin Cause Tendon Rupture?
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3 min read
In 2008, the U.S. Food and Drug Administration (FDA) issued a black box warning for levofloxacin and other fluoroquinolone antibiotics due to a serious risk of tendon inflammation and rupture. The answer to **why does levofloxacin cause tendon rupture** lies in its disruptive effects on the very building blocks and cells that maintain tendon health.